CALHM1 rabbit pAb

• Background :

  Calcium homeostasis modulator 1 (CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010]

• Description :

  Calcium homeostasis modulator 1 (CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear. [provided by RefSeq, Mar 2010],

• UniProt :

  Q8IU99

• Swiss Prot :

  Q8IU99

• Reactivity :

  Human; Rat

• Immunogen :

  Synthetic Peptide of CALHM1 AA range: 204-254

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF

• Dilution :

  WB: 1:500-1000 IHC: 1:200-500

• Molecular Weight :

  40kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  40kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein . Colocalizes with HSPA5 at the endoplasmic reticulum (PubMed:18585350) . Localizes to the basolateral membrane of epithelial cells including taste cells (By similarity) . .

• Other Product Names :

  Calcium homeostasis modulator protein 1; Protein FAM26C

• Gene ID (Human) :

  255022