GM130 rabbit pAb

• Background :

  The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs) . Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010]

• Description :

  The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010],

• Product Name Alternative :

  Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; Golgin-95)

• UniProt :

  Q08379

• Swiss Prot :

  Q08379

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human GM130

• Target :

  GM130

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  112-130kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  112-130kD

• Fragment :

  IgG

• Subcellular Location :

  Golgi apparatus, cis-Golgi network membrane ; Peripheral membrane protein ; Cytoplasmic side . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton, spindle pole . Associates with the mitotic spindle during mitosis (PubMed:26165940) . .

• Other Product Names :

  Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; Golgin-95)

• Gene ID (Human) :

  2801