IDE/Insulin Degrading Enzyme Mouse mAb

• Background :

  Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.

• Description :

  Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.

• Product Name Alternative :

  Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN

• UniProt :

  P14735

• Swiss Prot :

  P14735

• Reactivity :

  Human

• Immunogen :

  Synthetic Peptide

• Clonality :

  Monoclonal

• Source :

  Mouse

• Applications :

  WB, IHC

• Concentration :

  1mg/mL

• Dilution :

  WB 1:1,000 IHC 1:200

• Buffer :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Molecular Weight :

  118kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  118kDa

• Fragment :

  IgG1

• Subcellular Location :

  Cell membrane, Cytoplasm, Membrane, Secreted

• Other Product Names :

  Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN

• Gene ID (Human) :

  3416