A-actinin (4A12) Mouse mAb

• Background :

  α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.

• Description :

  α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.

• Product Name Alternative :

  Actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody

• UniProt :

  P12814

• Swiss Prot :

  P12814

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Recombinant Protein

• Clonality :

  Monoclonal

• Source :

  Mouse

• Applications :

  IHC

• Concentration :

  1mg/mL

• Dilution :

  IHC 1:100-200

• Buffer :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Molecular Weight :

  103kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  103kDa

• Fragment :

  IgG1

• Subcellular Location :

  Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane

• Other Product Names :

  Actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody

• Gene ID (Human) :

  87