AASS rabbit pAb

• Background :

  This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  AASS; Alpha-aminoadipic semialdehyde synthase; mitochondrial; LKR/SDH

• UniProt :

  Q9UDR5

• Swiss Prot :

  Q9UDR5

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human AASS. AA range:251-300

• Target :

  AASS

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  102kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  102kD

• Fragment :

  IgG

• Subcellular Location :

  Mitochondrion .

• Other Product Names :

  AASS; Alpha-aminoadipic semialdehyde synthase; mitochondrial; LKR/SDH

• Gene ID (Human) :

  10157