AChRα5 rabbit pAb

• Background :

  The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2) .[provided by RefSeq, Jun 2010]

• Description :

  The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2). [provided by RefSeq, Jun 2010],

• Product Name Alternative :

  CHRNA5; NACHRA5; Neuronal acetylcholine receptor subunit alpha-5

• UniProt :

  P30532

• Swiss Prot :

  P30532

• Reactivity :

  Human; Mouse; Rat; Monkey

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human AChRalpha5. AA range:166-215

• Target :

  AChRα5

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  53kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  53kD

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

• Other Product Names :

  CHRNA5; NACHRA5; Neuronal acetylcholine receptor subunit alpha-5

• Gene ID (Human) :

  1138