C1q-B rabbit pAb

• Background :

  This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq, Jul 2008],

• UniProt :

  P02746

• Swiss Prot :

  P02746

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human C1QB. AA range:161-210

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; Flow Cyt; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; Flow Cyt 1:50-200; IHC-p 1:100-500; IF/ICC 1:100-500; ELISA 1:5000-20000

• Molecular Weight :

  28kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  28kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted.

• Other Product Names :

  C1QB; Complement C1q subcomponent subunit B

• Gene ID (Human) :

  713