Cytochrome b5 rabbit pAb

• Background :

  The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

• Description :

  The protein encoded by this gene is a membrane-bound Cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],

• Product Name Alternative :

  CYB5A; CYB5; Cytochrome b5; Microsomal cytochrome b5 type A; MCB5

• UniProt :

  P00167

• Swiss Prot :

  P00167

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human CYB5. AA range:61-110

• Target :

  Cytochrome b5

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  15kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  15kD

• Fragment :

  IgG

• Subcellular Location :

  [Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.; [Isoform 2]: Cytoplasm.

• Other Product Names :

  CYB5A; CYB5; Cytochrome b5; Microsomal cytochrome b5 type A; MCB5

• Gene ID (Human) :

  1528