MIF rabbit pAb

• Background :

  This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008],

• UniProt :

  P14174

• Swiss Prot :

  P14174

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MIF. AA range:25-74

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IF; WB; IHC; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

• Molecular Weight :

  12kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  12kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted . Cytoplasm . Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens. .

• Other Product Names :

  MIF; GLIF; MMIF; Macrophage migration inhibitory factor; MIF; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; Phenylpyruvate tautomerase

• Gene ID (Human) :

  4282