Synphilin-1 rabbit pAb

• Background :

  This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

• Description :

  This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],

• Product Name Alternative :

  SNCAIP; Synphilin-1; Sph1; Alpha-synuclein-interacting protein

• UniProt :

  Q9Y6H5

• Swiss Prot :

  Q9Y6H5

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human Synphilin-1. AA range:797-846

• Target :

  Synphilin-1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  100kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  100kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Detected in cytoplasmic inclusion bodies, together with SNCA.

• Other Product Names :

  SNCAIP; Synphilin-1; Sph1; Alpha-synuclein-interacting protein

• Gene ID (Human) :

  9627