SYT rabbit pAb

• Background :

  Disease:A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t (X;18) (p11.2; q11.2) . The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency) ., similarity:Belongs to the SS18 family., tissue specificity:Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.

• Description :

  Disease: A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t (X;18) (p11. 2;q11. 2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). similarity: Belongs to the SS18 family. tissue specificity: Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.

• UniProt :

  Q15532

• Swiss Prot :

  Q15532

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human SSXT. AA range:1-50

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  45kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  45kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  SS18; SSXT; SYT; Protein SSXT; Protein SYT; Synovial sarcoma translocated to X chromosome protein

• Gene ID (Human) :

  6760