MACC1 rabbit pAb

• Background :

  MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) -HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]) .[supplied by OMIM, Mar 2009]

• Description :

  MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al. 2009 [PubMed 19098908]). [supplied by OMIM, Mar 2009],

• Product Name Alternative :

  MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5

• UniProt :

  Q6ZN28

• Swiss Prot :

  Q6ZN28

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1. AA range:411-460

• Target :

  MACC1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  97kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  97kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus . Mainly found in the cytoplasm in non-metastasizing tumors.

• Other Product Names :

  MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5

• Gene ID (Human) :

  346389