ME3 rabbit pAb

• Background :

  Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP (+) -dependent isoform, a mitochondrial NADP (+) -dependent isoform, and a mitochondrial NAD (+) -dependent isoform. This gene encodes a mitochondrial NADP (+) -dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

• Description :

  Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP (+)-dependent isoform, a mitochondrial NADP (+)-dependent isoform, and a mitochondrial NAD (+)-dependent isoform. This gene encodes a mitochondrial NADP (+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],

• UniProt :

  Q16798

• Swiss Prot :

  Q16798

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ME3. AA range:545-594

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight :

  67kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  67kD

• Fragment :

  IgG

• Subcellular Location :

  Mitochondrion matrix.

• Other Product Names :

  ME3; NADP-dependent malic enzyme; mitochondrial; NADP-ME; Malic enzyme 3

• Gene ID (Human) :

  10873