NCoA-7 rabbit pAb

• Background :

  Function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA., similarity:Belongs to the OXR1 family., similarity:Contains 1 LysM repeat., similarity:Contains 1 TLD domain., subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT., tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.

• Description :

  Function: Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA. similarity: Belongs to the OXR1 family. similarity: Contains 1 LysM repeat. similarity: Contains 1 TLD domain. subunit: Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT. tissue specificity: Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.

• UniProt :

  Q8NI08

• Swiss Prot :

  Q8NI08

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human NCOA7. AA range:422-471

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  106kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  106kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  NCOA7; ERAP140; ESNA1; Nbla00052; Nbla10993; Nuclear receptor coactivator 7; 140 kDa estrogen receptor-associated protein; Estrogen nuclear receptor coactivator 1

• Gene ID (Human) :

  135112