APLF (phospho Ser116) rabbit pAb

• Background :

  C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]) .[supplied by OMIM, Mar 2008]

• Description :

  C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al. 2007 [PubMed 17353262]). [supplied by OMIM, Mar 2008],

• UniProt :

  Q8IW19

• Swiss Prot :

  Q8IW19

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human APLF around the phosphorylation site of Ser116. AA range:82-131

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Chromosome . Cytoplasm, cytosol . Localizes to DNA damage sites (PubMed:18474613, PubMed:18172500, PubMed:21211721, PubMed:23689425) . Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers (PubMed:18172500) . .

• Other Product Names :

  APLF; C2orf13; PALF; XIP1; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1

• Gene ID (Human) :

  200558