NACAD rabbit pAb

• Background :

  Function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER) . May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) ., similarity:Belongs to the NAC-alpha family., similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.

• Description :

  Function: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). similarity: Belongs to the NAC-alpha family. similarity: Contains 1 NAC-A/B (NAC-alpha/beta) domain.

• Product Name Alternative :

  NACAD; KIAA0363; NAC-alpha domain-containing protein 1

• UniProt :

  O15069

• Swiss Prot :

  O15069

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425

• Target :

  NACAD

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  140kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  140kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus .

• Other Product Names :

  NACAD; KIAA0363; NAC-alpha domain-containing protein 1

• Gene ID (Human) :

  23148