T2R45 rabbit pAb

• Background :

  Function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5., miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli., similarity:Belongs to the G-protein coupled receptor T2R family., tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

• Description :

  Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli. similarity: Belongs to the G-protein coupled receptor T2R family. tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

• Product Name Alternative :

  TAS2R45; GPR59; Taste receptor type 2 member 45; T2R45; G-protein coupled receptor 59

• UniProt :

  P59539

• Swiss Prot :

  P59539

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human TAS2R45. AA range:221-270

• Target :

  T2R45

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  35kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  35kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane; Multi-pass membrane protein.

• Other Product Names :

  TAS2R45; GPR59; Taste receptor type 2 member 45; T2R45; G-protein coupled receptor 59

• Gene ID (Human) :

  259291