MIP-T3 rabbit pAb

• Background :

  Function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules., similarity:Belongs to the TRAF3IP1 family., subcellular location:Microtubules., subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1., tissue specificity:Ubiquitous.

• Description :

  Function: Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. similarity: Belongs to the TRAF3IP1 family. subcellular location: Microtubules. subunit: Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1. tissue specificity: Ubiquitous.

• UniProt :

  Q8TDR0

• Swiss Prot :

  Q8TDR0

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MIPT3. AA range:221-270

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  78kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  78kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900) . In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268) . .

• Other Product Names :

  TRAF3IP1; MIPT3; TRAF3-interacting protein 1; Interleukin-13 receptor alpha 1-binding protein 1; Microtubule-interacting protein associated with TRAF3; MIP-T3

• Gene ID (Human) :

  26146