IRAK-1 (phospho Thr209) rabbit pAb

• Background :

  This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1

• UniProt :

  P51617

• Swiss Prot :

  P51617

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr209. AA range:175-224

• Target :

  IRAK-1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  77kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  77kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity) . .

• Other Product Names :

  IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1

• Gene ID (Human) :

  3654