MAZ rabbit pAb

• Background :

  Function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors., similarity:Contains 6 C2H2-type zinc fingers., subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures., subunit:Interacts with BPTF., tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level) .

• Description :

  Function: May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. similarity: Contains 6 C2H2-type zinc fingers. subcellular location: In brains of Alzheimer disease patients, present in a plaque-like structures. subunit: Interacts with BPTF. tissue specificity: Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).

• UniProt :

  P56270

• Swiss Prot :

  P56270

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MAZ. AA range:159-208

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Molecular Weight :

  48kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  48kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . In brains of Alzheimer disease patients, present in a plaque-like structures.

• Other Product Names :

  MAZ; ZNF801; Myc-associated zinc finger protein; MAZI; Pur-1; Purine-binding transcription factor; Transcription factor Zif87; ZF87; Zinc finger protein 801

• Gene ID (Human) :

  4150