Mcl-1 (phospho Ser159) rabbit pAb
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Mcl-1 (phospho Ser159) rabbit pAb
Background :
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]Description :
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010],Product Name Alternative :
MCL1; BCL2L3; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EATUniProt :
Q07820Swiss Prot :
Q07820Reactivity :
Human; MouseImmunogen :
The antiserum was produced against synthesized peptide derived from human MCL1 around the phosphorylation site of Ser159. AA range:125-174Target :
Mcl-1Clonality :
PolyclonalSource :
RabbitApplications :
WB; ELISA; IHCConcentration :
1 mg/mlDilution :
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000Buffer :
-20°C/1 yearMolecular Weight :
About 40kd in human,39kd in mouse and ratStorage Conditions :
-20°C/1 yearObserved Molecular Weight :
About 40kd in human,39kd in mouse and ratFragment :
IgGSubcellular Location :
Membrane ; Single-pass membrane protein . Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.Other Product Names :
MCL1; BCL2L3; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EATGene ID (Human) :
4170
