ZDHHC2 rabbit pAb

• Background :

  Catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA., disease:Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer., domain:The DHHC domain is required for palmitoyltransferase activity., function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95., similarity:Belongs to the DHHC palmitoyltransferase family., similarity:Contains 1 DHHC-type zinc finger., tissue specificity:Ubiquitously expressed. Reduced expression in colorectal cancers.

• Description :

  Catalytic activity: Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA. Disease: Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer. Domain: The DHHC domain is required for palmitoyltransferase activity. function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95. similarity: Belongs to the DHHC palmitoyltransferase family. similarity: Contains 1 DHHC-type zinc finger. tissue specificity: Ubiquitously expressed. Reduced expression in colorectal cancers.

• Product Name Alternative :

  ZDHHC2; REAM; REC; ZNF372; Palmitoyltransferase ZDHHC2; Reduced expression associated with metastasis protein; Ream; Reduced expression in cancer protein; Rec; Zinc finger DHHC domain-containing protein 2; DHHC-2; Zinc finger protein 372

• UniProt :

  Q9UIJ5

• Swiss Prot :

  Q9UIJ5

• Reactivity :

  Human; Mouse; Rat; Monkey

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ZDHHC2. AA range:61-110

• Target :

  ZDHHC2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  42kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  42kD

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, synapse, postsynaptic density . Postsynaptic recycling endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Translocates to postsynaptic density when synaptic activity decreases. .

• Other Product Names :

  ZDHHC2; REAM; REC; ZNF372; Palmitoyltransferase ZDHHC2; Reduced expression associated with metastasis protein; Ream; Reduced expression in cancer protein; Rec; Zinc finger DHHC domain-containing protein 2; DHHC-2; Zinc finger protein 372

• Gene ID (Human) :

  51201