ASAH3L rabbit pAb

• Background :

  The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]) .[supplied by OMIM, Jul 2010]

• Description :

  The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al. 2006 [PubMed 16940153]). [supplied by OMIM, Jul 2010],

• Product Name Alternative :

  ACER2; ASAH3L; PP11646; Alkaline ceramidase 2; AlkCDase 2; Alkaline CDase 2; haCER2; Acylsphingosine deacylase 3-like; N-acylsphingosine amidohydrolase 3-like

• UniProt :

  Q5QJU3

• Swiss Prot :

  Q5QJU3

• Reactivity :

  Human; Mouse; Monkey

• Immunogen :

  Synthesized peptide derived from ASAH3L . at AA range: 50-130

• Target :

  ASAH3L

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  33kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  33kD

• Fragment :

  IgG

• Subcellular Location :

  Golgi apparatus membrane ; Multi-pass membrane protein .

• Other Product Names :

  ACER2; ASAH3L; PP11646; Alkaline ceramidase 2; AlkCDase 2; Alkaline CDase 2; haCER2; Acylsphingosine deacylase 3-like; N-acylsphingosine amidohydrolase 3-like

• Gene ID (Human) :

  340485