PACAP rabbit pAb

• Background :

  Function:May be involved in regulation of apoptosis., induction:Down-regulated in primary B-cells early after ligand-stimulated activation., subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus., subunit:Isoform 2 interacts with CASP2 and CASP9., tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.

• Description :

  Function: May be involved in regulation of apoptosis. induction: Down-regulated in primary B-cells early after ligand-stimulated activation. subcellular location: In (PubMed: 11350957) diffuse granular localization in the cytoplasm surrounding the nucleus. subunit: Isoform 2 interacts with CASP2 and CASP9. tissue specificity: Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.

• UniProt :

  Q8WU39

• Swiss Prot :

  Q8WU39

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthetic peptide from human protein at AA range: 1-50

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p 1:50-200, ELISA 1:10000-20000

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  [Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957) .

• Other Product Names :

  Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein; pERp1; Proapoptotic caspase adapter protein)

• Gene ID (Human) :

  51237