Parafibromin rabbit pAb

• Background :

  This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

• Description :

  This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009],

• Product Name Alternative :

  Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)

• UniProt :

  Q6P1J9

• Swiss Prot :

  Q6P1J9

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human Parafibromin. at AA range: 51-100

• Target :

  Parafibromin

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000, ELISA 1:10000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  60kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  60kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)

• Gene ID (Human) :

  79577