B4GT4 rabbit pAb

CAT:
855-ES9448-02
Size:
100 µL
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
B4GT4 rabbit pAb - image 1

B4GT4 rabbit pAb

  • Background :

    This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcrip
  • Description :

    This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcrip
  • UniProt :

    O60513
  • Swiss Prot :

    O60513
  • Reactivity :

    Human; Mouse; Rat
  • Immunogen :

    Synthesized peptide derived from part region of human protein
  • Target :

    B4GT4
  • Clonality :

    Polyclonal
  • Source :

    Rabbit
  • Applications :

    WB; ELISA
  • Concentration :

    1 mg/ml
  • Dilution :

    WB 1:500-2000 ELISA 1:5000-20000
  • Buffer :

    -20°C/1 year
  • Molecular Weight :

    37kD
  • Storage Conditions :

    -20°C/1 year
  • Observed Molecular Weight :

    37kD
  • Fragment :

    IgG
  • Subcellular Location :

    Golgi apparatus membrane ; Single-pass type II membrane protein . Secreted .
  • Gene ID (Human) :

    8702

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