SH3G3 rabbit pAb

• Background :

  Domain:An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes., function:Implicated in endocytosis. May recruit other proteins to membranes with high curvature., similarity:Belongs to the endophilin family., similarity:Contains 1 BAR domain., similarity:Contains 1 SH3 domain., subcellular location:Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons., subunit:Interacts with ARC (By similarity) . Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo., tissue specificity:Brain and testis.

• Description :

  Domain: An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes. function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature. similarity: Belongs to the endophilin family. similarity: Contains 1 BAR domain. similarity: Contains 1 SH3 domain. subcellular location: Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons. subunit: Interacts with ARC (By similarity). Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo. tissue specificity: Brain and testis.

• UniProt :

  Q99963

• Swiss Prot :

  Q99963

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Target :

  SH3G3

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  38kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  38kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons. .

• Gene ID (Human) :

  6457