Iba1 rabbit pAb

• Background :

  This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]

• Description :

  This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],

• UniProt :

  P55008

• Swiss Prot :

  P55008

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Target :

  AIF1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. IF 1:100-300 Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  16kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  16kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. .

• Gene ID (Human) :

  199