WIPI2 (phospho-Ser413) rabbit pAb

• Background :

  WD repeat domain, phosphoinositide interacting 2 (WIPI2) Homo sapiens WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]) .[supplied by OMIM, Mar 2008]

• Description :

  WD repeat domain, phosphoinositide interacting 2 (WIPI2) Homo sapiens WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al. 2004 [PubMed 15602573]). [supplied by OMIM, Mar 2008],

• UniProt :

  Q9Y4P8

• Swiss Prot :

  Q9Y4P8

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized phosho peptide around human WIPI2 (Ser413)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000

• Molecular Weight :

  49kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  49kD

• Fragment :

  IgG

• Subcellular Location :

  Preautophagosomal structure membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to omegasomes membranes which are endoplasmic reticulum connected structures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P. .

• Other Product Names :

  WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)

• Gene ID (Human) :

  26100