KLK15 rabbit pAb

• Background :

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

• Description :

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

• UniProt :

  Q9H2R5

• Swiss Prot :

  Q9H2R5

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human KLK15 AA range: 20-100

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; WB

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p 1:50-200, WB 1:500-2000

• Molecular Weight :

  35kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  35kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted .

• Other Product Names :

  Kallikrein-15 (EC 3.4.21.-; ACO protease)

• Gene ID (Human) :

  55554