GUC1A rabbit pAb

• Background :

  This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Description :

  This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

• UniProt :

  P43080

• Swiss Prot :

  P43080

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human GUC1A AA range: 63-113

• Target :

  GUC1A

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Membrane; Lipid-anchor . Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Present at higher levels in cone than in rod outer segments (PubMed:9620085) . Subcellular location is not affected by light or dark conditions. .

• Gene ID (Human) :

  2978