KCNK9 (TASK-3) rabbit pAb

• Background :

  This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Description :

  This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

• UniProt :

  Q9NPC2

• Swiss Prot :

  Q9NPC2

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthetic Peptide of KCNK9 (TASK-3) AA range: 220-270

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000, IHC 1:100-200

• Molecular Weight :

  42kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  42kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Multi-pass membrane protein .

• Other Product Names :

  Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K (+) channel 3; Two pore potassium channel KT3.2; Two pore K (+) channel KT3.2)

• Gene ID (Human) :

  51305