SSH3 (phospho-Ser37) rabbit pAb

• Background :

  The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .[supplied by OMIM, Mar 2008]

• Description :

  The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al. 2002 [PubMed 11832213]). [supplied by OMIM, Mar 2008],

• UniProt :

  Q8TE77

• Swiss Prot :

  Q8TE77

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized phosho peptide around human SSH3 (Ser37)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000

• Molecular Weight :

  74kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  74kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytoskeleton . Nucleus .

• Other Product Names :

  Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)

• Gene ID (Human) :

  54961