PDE6G Rabbit pAb

• Background :

  This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]

• Description :

  This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],

• Product Name Alternative :

  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma; EC 3.1.4.35)

• UniProt :

  P18545

• Swiss Prot :

  P18545

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human PDE6G AA range: 10-90

• Target :

  PDE6G

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Plasma membrane, photoreceptor disc membrane

• Other Product Names :

  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma; EC 3.1.4.35)

• Gene ID (Human) :

  5148