Histone H2A.X (Phospho Thr120) rabbit pAb

• Background :

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]

• Description :

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

• Product Name Alternative :

  H2AFX; H2AX; Histone H2A.x; H2a/x

• UniProt :

  P16104

• Swiss Prot :

  P16104

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthetic Peptide of Histone H2A.X (Phospho Thr120)

• Target :

  Histone H2A.X

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Dilution :

  WB: 1:1000-2000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  15kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  15kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Chromosome .

• Other Product Names :

  H2AFX; H2AX; Histone H2A.x; H2a/x

• Gene ID (Human) :

  3014