PNK1 (phospho-Ser114/Thr118) rabbit pAb

• Background :

  This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010]

• Description :

  This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay. [provided by RefSeq, Sep 2010],

• UniProt :

  Q96T60

• Swiss Prot :

  Q96T60

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized phosho peptide around human PNK1 (Ser114 and Thr118)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight :

  57kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  57kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Chromosome . Localizes to site of double-strand breaks. .

• Other Product Names :

  Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2' (3') -polynucleotidase) ; Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78) ]

• Gene ID (Human) :

  11284