α-E-Catenin (phospho-Ser652) rabbit pAb

• Background :

  Catenin alpha 1 (CTNNA1) Homo sapiens This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]

• Description :

  Catenin alpha 1 (CTNNA1) Homo sapiens This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016],

• Product Name Alternative :

  Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)

• UniProt :

  P35221

• Swiss Prot :

  P35221

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized phosho peptide around human α-E-Catenin (Ser652)

• Target :

  α-E-Catenin

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  100kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  100kD

• Fragment :

  IgG

• Subcellular Location :

  [Isoform 1]: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.; [Isoform 3]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .

• Other Product Names :

  Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)

• Gene ID (Human) :

  1495