STX5 rabbit pAb

• Background :

  This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

• Description :

  This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

• Product Name Alternative :

  Syntaxin-5

• UniProt :

  Q13190

• Swiss Prot :

  Q13190

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human STX5 AA range: 233-283

• Target :

  STX5

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  38kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  38kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type IV membrane protein . Golgi apparatus membrane . Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae. .

• Other Product Names :

  Syntaxin-5

• Gene ID (Human) :

  6811