SC5AC rabbit pAb

• Background :

  Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+) -coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+) -coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]) .[supplied by OMIM, Dec 2008]

• Description :

  Normal blood lactate is maintained at about 1. 5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al. 2007 [PubMed 17692818]). [supplied by OMIM, Dec 2008],

• UniProt :

  Q1EHB4

• Swiss Prot :

  Q1EHB4

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human SC5AC AA range: 84-134

• Target :

  SC5AC

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Apical cell membrane ; Multi-pass membrane protein . Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity) . .

• Gene ID (Human) :

  159963