CaMK2 (Phospho-Thr286) Rabbit pAb

• Background :

  The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]

• Description :

  The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

• Product Name Alternative :

  Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta; CaMK-II subunit delta; EC 2.7.11.17)

• UniProt :

  Q9UQM7/Q13557

• Swiss Prot :

  Q9UQM7/Q13557

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)

• Target :

  CaMK2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000, ELISA (peptide) 1:5000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  54kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  54kD

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .

• Other Product Names :

  Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta; CaMK-II subunit delta; EC 2.7.11.17)

• Gene ID (Human) :

  817