HNF1α (phospho-Ser247) rabbit pAb

• Background :

  The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

• Description :

  The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

• UniProt :

  P20823

• Swiss Prot :

  P20823

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized phosho peptide around human HNF1α (Ser247)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000

• Molecular Weight :

  69kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  69kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)

• Gene ID (Human) :

  6927