ENOS (Phospho-Ser1179) rabbit pAb

• Background :

  Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

• Description :

  Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

• UniProt :

  P29474

• Swiss Prot :

  P29474

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human eNOS (Phospho-Ser1179)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; WB

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p 1:50-200, WB 1:500-2000

• Molecular Weight :

  130-140kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  130-140kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.

• Other Product Names :

  Nitric oxide synthase, endothelial (EC 1.14.13.39; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII)

• Gene ID (Human) :

  4846