C-Myb (Acetyl Lys480) rabbit pAb

• Background :

  Domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression., function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells., PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation., PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation., similarity:Contains 3 HTH myb-type DNA-binding domains., subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.

• Description :

  Domain: Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression. function: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. PTM: Phosphorylated by NLK on multiple sites, which induces proteasomal degradation. PTM: Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. similarity: Contains 3 HTH myb-type DNA-binding domains. subunit: Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.

• UniProt :

  P10242

• Swiss Prot :

  P10242

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human c-Myb (Acetyl Lys480)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000 ELISA 1:5000-20000

• Molecular Weight :

  70kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  70kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  Transcriptional activator Myb (Proto-oncogene c-Myb)

• Gene ID (Human) :

  4602