AHR rabbit pAb

• Background :

  The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]

• Description :

  The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as Cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],

• UniProt :

  P35869

• Swiss Prot :

  P35869

• Reactivity :

  Human; Mouse; Rat; Fish

• Immunogen :

  Synthesized peptide derived from human AHR AA range: 408-458

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IF

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IF/ICC 1:100-500

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. .

• Gene ID (Human) :

  196