Caspase 9 Mouse mAb

• Background :

  Caspase-9 is an initiator caspase, encoded by the CASP9 gene.Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) .

• Description :

  Caspase-9 is an initiator caspase, encoded by the CASP9 gene. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP).

• Product Name Alternative :

  APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody

• UniProt :

  P55211

• Swiss Prot :

  P55211

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Synthetic Peptide

• Clonality :

  Monoclonal

• Source :

  Mouse

• Applications :

  WB, IP, IF

• Concentration :

  1mg/mL

• Dilution :

  WB 1:1,000-5,000 IP 1:200 IF 1:100-200

• Buffer :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Molecular Weight :

  47 (51)kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  47 (51) kDa

• Fragment :

  IgG1

• Subcellular Location :

  Cytosol, Mitochondrion, Nucleus

• Other Product Names :

  APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody

• Gene ID (Human) :

  842