NBR1 (7C3) Mouse mAb

• Background :

  NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.

• Description :

  NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.

• Product Name Alternative :

  1A13B, MIG19, Nbr1

• UniProt :

  Q14596

• Swiss Prot :

  Q14596

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant Protein

• Clonality :

  Monoclonal

• Source :

  Mouse

• Applications :

  IHC

• Concentration :

  1mg/mL

• Dilution :

  IHC 1:100-200

• Buffer :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Molecular Weight :

  120kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  120kDa

• Fragment :

  IgG1

• Subcellular Location :

  Cytoplasm, Cytoplasmic vesicle, Lysosome

• Other Product Names :

  1A13B, MIG19, Nbr1

• Gene ID (Human) :

  4077