ATG5 (3C7) Mouse mAb

• Background :

  Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

• Description :

  Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

• Product Name Alternative :

  APG5, APG5L, ASP, Autophagy protein 5 antibody

• UniProt :

  Q9H1Y0

• Swiss Prot :

  Q9H1Y0

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant Protein

• Clonality :

  Monoclonal

• Source :

  Mouse

• Applications :

  WB, IHC

• Concentration :

  1mg/mL

• Dilution :

  WB 1:5,000-10,000 IHC 1:100-200

• Buffer :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Molecular Weight :

  55kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  55kDa

• Fragment :

  IgG1

• Subcellular Location :

  Cytoplasm, Membrane

• Other Product Names :

  APG5, APG5L, ASP, Autophagy protein 5 antibody

• Gene ID (Human) :

  9494