Cleaved-ITI-H2 (D702) rabbit pAb

• Background :

  The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]) .[supplied by OMIM, Nov 2009]

• Description :

  The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al. 1987 [PubMed 2446322]; Himmelfarb et al. 2004 [PubMed 14744536]). [supplied by OMIM, Nov 2009],

• Product Name Alternative :

  ITIH2; IGHEP2; Inter-alpha-trypsin inhibitor heavy chain H2; ITI heavy chain H2; ITI-HC2; Inter-alpha-inhibitor heavy chain 2; Inter-alpha-trypsin inhibitor complex component II; Serum-derived hyaluronan-associated protein; SHAP

• UniProt :

  P19823

• Swiss Prot :

  P19823

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ITIH2. AA range:653-702

• Target :

  ITI-H2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  72kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  72kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted.

• Other Product Names :

  ITIH2; IGHEP2; Inter-alpha-trypsin inhibitor heavy chain H2; ITI heavy chain H2; ITI-HC2; Inter-alpha-inhibitor heavy chain 2; Inter-alpha-trypsin inhibitor complex component II; Serum-derived hyaluronan-associated protein; SHAP

• Gene ID (Human) :

  3698