CRM1 (Acetyl Lys568) rabbit pAb

• Background :

  This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES) -dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]

• Description :

  This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],

• Product Name Alternative :

  XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog

• UniProt :

  O14980

• Swiss Prot :

  O14980

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.

• Target :

  CRM1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  125kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  125kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.

• Other Product Names :

  XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog

• Gene ID (Human) :

  7514