GSK3α/β (phospho Tyr279/216) rabbit pAb

• Background :

  Glycogen synthase kinase 3 alpha (GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011]

• Description :

  Glycogen synthase kinase 3 alpha (GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],

• Product Name Alternative :

  GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B

• UniProt :

  P49840/P49841

• Swiss Prot :

  P49840/P49841

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human GSK3 alpha/beta around the phosphorylation site of Tyr279/216. AA range:246-295

• Target :

  GSK3α/β

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IF; WB; IHC; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  51,46kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  51,46kD

• Fragment :

  IgG

• Subcellular Location :

  Mitochondrion, cytosol, beta-catenin destruction complex, postsynapse

• Other Product Names :

  GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B

• Gene ID (Human) :

  2931